abstract：BACKGROUND AND OBJECTIVE:Short-pulse solid-state lasers have recently received much attention as new coherent light sources for medical applications, but steady transmission of their high-energy output pulses through a solid quartz fiber is difficult because of the onset of laser-induced breakdown. We previously demons...

journal_title：Lasers in surgery and medicine

authors： Sato S,Shi YW,Matsuura Y,Miyagi M,Ashida H

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Terawatt (TW) lasers have become commonplace since the development of the chirped-pulse amplification method using Ti:sapphire and Nd:glass laser rods. We have measured the minimum visible lesion (MVL) thresholds for porcine1The animals involved in this study were procured, maintained, and use...

journal_title：Lasers in surgery and medicine

authors： Kumru SS,Cain CP,Noojin GD,Cooper MF,Imholte ML,Stolarski DJ,Cox DD,Crane CC,Rockwell BA

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Facial teleangectasias can be a relevant cosmetic problem, which the patient usually hides with a thick layer of makeup. This study will describe the response on these vascular lesions using the intense pulsed light (IPL) source. METHODS:Five hundred eighteen consecutive patients were treated...

journal_title：Lasers in surgery and medicine

authors： Clementoni MT,Gilardino P,Muti GF,Signorini M,Pistorale A,Morselli PG,Cavina C

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:As a potential therapy for malignant glioma, we tested the phthalocyanine photosensitizer Pc 4 for: (1) rapid clearance from the vasculature, (2) specificity for glioma, and (3) tumoricidal photosensitizing capability. STUDY DESIGN/MATERIALS AND METHODS:Parenchymal injection of U87 cells into...

journal_title：Lasers in surgery and medicine

authors： George JE 3rd,Ahmad Y,Varghai D,Li X,Berlin J,Jackowe D,Jungermann M,Wolfe MS,Lilge L,Totonchi A,Morris RL,Peterson A,Lust WD,Kenney ME,Hoppel CL,Sun J,Oleinick NL,Dean D

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Variable square pulse (VSP) Er:YAG laser should be quicker than older Er:YAG lasers. The objectives were: (1) comparison of VSP laser and mechanical handpiece efficacy for apicectomy and (2) determination of optimal pulse width/energy/frequency combination. STUDY DESIGN/MATERIALS AND METHODS:...

journal_title：Lasers in surgery and medicine

authors： Grgurević J,Grgurević L,Miletić I,Karlović Z,Krmek SJ,Anić I

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Intralipid (IP) is a scatterer extensively used in the building of phantoms for Biomedical Optics measurements. Recently, deviations from the linearity have been shown for the concentration scaling law of the scattering coefficient of IP water solutions at visible wavelengths. In this work thi...

journal_title：Lasers in surgery and medicine

authors： Autiero M,Liuzzi R,Riccio P,Roberti G

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Hypervascular skin lesions (HVSL) are treated with medical lasers characterized by a variety of parameters such as wavelength lambda, pulse duration t(p), and radiant exposure E that can be adjusted for different pathology and blood vessel size. Treatment parameters have been optimized assumin...

journal_title：Lasers in surgery and medicine

authors： Kimel S,Choi B,Svaasand LO,Lotfi J,Viator JA,Nelson JS

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:To produce controlled, spatially confined thermal effects in dermis. STUDY DESIGNS/MATERIALS AND METHODS:A 1 W, 1,500 nm fiber-coupled diode laser was focused with a high numerical aperture (NA) objective to achieve a tight optical focus within the upper dermis of skin held in contact with a ...

journal_title：Lasers in surgery and medicine

authors： Khan MH,Sink RK,Manstein D,Eimerl D,Anderson RR

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Laser-induced photo thermal damage has been combined with photodynamic therapy (PDT) using a systemic photosensitiser to treat vascular lesions. The efficacy of PDT using systemic 5-aminolaevulinic acid (5-ALA) as the photosensitiser and pulsed dye laser (PDL) as the light source in port wine ...

journal_title：Lasers in surgery and medicine

authors： Evans AV,Robson A,Barlow RJ,Kurwa HA

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Carbon dioxide (CO(2)) laser resurfacing is primarily performed on photodamaged facial skin where patients are further exposed to ultraviolet radiation (UVR) postoperatively. We examined whether pre- and postoperative UVR influences the development of CO(2) laser-induced side effects. STUDY D...

journal_title：Lasers in surgery and medicine

authors： Hedelund L,Haedersdal M,Egekvist H,Heidenheim M,Hans CW,Poulsen T

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The purpose of this in vitro study is to evaluate the use of the KTP (potassium-titanyl-phosphate) 532 nm laser for future use in endovaporization of large choroidal melanomas. STUDY DESIGN/MATERIALS AND METHODS:A KTP 532 nm green laser coupled to a 0.3 mm fiberoptic probe was used to perform...

journal_title：Lasers in surgery and medicine

authors： Mattes D,Reich EM,Muellner K,Langmann G

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:It is established that both pulsed Nd:YAG (1,064 nm) and continuous diode (810 nm) dental lasers kill pathogenic bacteria (laser antisepsis), but a quantitative method for determining clinical dosimetry does not exist. The purpose of this study was to develop a method to quantify the efficacy ...

journal_title：Lasers in surgery and medicine

authors： Harris DM,Yessik M

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Low level laser irradiation (LLLI) is used to promote wound healing. Molecularly it is known to stimulate mitochondrial membrane potential (MMP), cytokine secretion, and cell proliferation. This study was designed to determine the influence of LLLI on the kinetics of MMP stimulation and decay,...

journal_title：Lasers in surgery and medicine

authors： Gavish L,Asher Y,Becker Y,Kleinman Y

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The difficulties typically encountered in studying the effects of restorations on tooth reinforcement are often due to the 3-dimensional (3D) nature of deformation. Therefore, electronic 3D-Speckle-Interferometry (3D-ESPI) was used to assess the impact of different restorative materials on the...

journal_title：Lasers in surgery and medicine

authors： Lang H,Rampado M,Müllejans R,Raab WH

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Attempts at using the pulsed dye laser (PDL) operating at 585 nm wavelength and 0.45 milliseconds pulse duration to treat leg veins have been notably unsuccessful. The aim of this study is to evaluate the efficacy and complications of the 595 nm long PDL in the treatment of leg veins. STUDY D...

journal_title：Lasers in surgery and medicine

authors： Kono T,Yamaki T,Erçöçen AR,Fujiwara O,Nozaki M

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:We evaluated the potential of combining laser excision with laser interstitial hyperthermia in order to improve the quality of life of patients with 3rd or 4th stage malignant head and neck tumours. STUDY DESIGN/MATERIALS AND METHODS:To evaluate the quality of life, we used the 4th version of...

journal_title：Lasers in surgery and medicine

authors： Smucler R,Mazánek J

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Keloids have been treated with flashlamp pulsed dye lasers (PDLs) with good results. We investigated whether PDL treatments induced keloid regression by decreasing growth factor-beta(1) (TGF-beta(1)) induction, thereby reducing fibroblast proliferation and collagen deposition. STUDY DESIGN/MA...

journal_title：Lasers in surgery and medicine

authors： Kuo YR,Jeng SF,Wang FS,Chen TH,Huang HC,Chang PR,Yang KD

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The conventional pulsed-dye laser (wavelength 585 nm, pulse duration 0.5 milliseconds) is seen as the standard treatment for port wine stains (PWS). Using the pulsed-dye laser at wavelengths of 590, 595, and 600 nm and at varying pulse durations of 1.5-40 milliseconds is one of the newest deve...

journal_title：Lasers in surgery and medicine

authors： Greve B,Raulin C

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:This work evaluates the application of a 810 nm diode laser operating in the range of 400-1,200 mW for bacterial reduction at periodontal treatment. The aim of this study is to examine the immediate effect of the diode medium power laser in reducing the bacterial concentration at periodontal po...

journal_title：Lasers in surgery and medicine

authors： Fontana CR,Kurachi C,Mendonça CR,Bagnato VS

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The aim of this clinical study was to evaluate the safety of local delivery of a photosensitizer followed by photodynamic therapy (PDT), to determine its effectiveness in reducing in-stent restenosis. STUDY DESIGN/PATIENTS AND METHODS:Porfimer sodium was administered via a local delivery cath...

journal_title：Lasers in surgery and medicine

authors： Usui M,Miyagi M,Fukasawa S,Hara T,Ueyama N,Nakajima H,Takata R,Sasame A,Tamura K,Naitou Y,Yamashina A

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:During transmyocardial laser revascularization (TMLR), multiple microembolic signals (MES) can be detected in cerebral arteries. We sought to characterize composition and clinical relevance of these MES and to evaluate strategies to reduce cerebral microembolization during TMLR. STUDY DESIGN/...

journal_title：Lasers in surgery and medicine

authors： Gerriets T,Grossherr M,Misfeld M,Nees U,Reusche E,Stolz E,Sievers HH,Kaps M,Kraatz EG

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In the last decade, many different kinds of therapies have emerged as a consequence of advances in the field of applied technology. It is known that low level laser therapy contributes to tissue healing; however, the use of photodynamic therapy (PDT) in healing and the scar formation processes...

journal_title：Lasers in surgery and medicine

authors： Silva JC,Lacava ZG,Kuckelhaus S,Silva LP,Neto LF,Sauro EE,Tedesco AC

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:To determine the true efficacy of the 308-nm excimer laser for the treatment of vitiligo, while taking into account confounding factors such as anatomic site of treatment, age, sex, skin type, MED, and duration of evolution of the vitiligo. STUDY DESIGN/MATERIALS AND METHODS:Thirty-five patie...

journal_title：Lasers in surgery and medicine

authors： Ostovari N,Passeron T,Zakaria W,Fontas E,Larouy JC,Blot JF,Lacour JP,Ortonne JP

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Whether light emitting diode (LED) irradiation has effects on "beta-amyloid (A beta) induced apoptosis," a leading hypothesis of the cause of Alzheimer's disease (AD), or not? STUDY DESIGN/MATERIALS AND METHODS:Monolayer cell cultures of PC12 were subjected to A beta or/and LED irradiation at...

journal_title：Lasers in surgery and medicine

authors： Duan R,Zhu L,Liu TC,Li Y,Liu J,Jiao J,Xu X,Yao L,Liu S

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Laser light of various wavelengths is being used for surgical procedures in otolaryngology. Apart from well-known fiber guided laser systems such as Nd:YAG- and Ho:YAG-lasers, newly developed diode-laser systems of different wavelengths have recently become popular in surgery. In order to comp...

journal_title：Lasers in surgery and medicine

authors： Janda P,Sroka R,Mundweil B,Betz CS,Baumgartner R,Leunig A

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Cosmeceuticals, chemical peels and collagen injections are used to rejuvenate skin, but none of these methods is effective or permanent. Recently, laser resurfacing has been found to be effective, but the incidence of side effects is relatively high. Two years ago, the non-ablative wrinkle red...

journal_title：Lasers in surgery and medicine

authors： Omi T,Kawana S,Sato S,Honda M

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Intra-operative identification of tumor by fluorescence may improve surgical resection or photodynamic therapy (PDT). A novel instrument was designed, constructed, and tested for this purpose. STUDY DESIGN/MATERIALS AND METHODS:The instrument was designed to provide high-resolution, multi-spe...

journal_title：Lasers in surgery and medicine

authors： Yang VX,Muller PJ,Herman P,Wilson BC

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:To test whether autofluorescence spectroscopy can be used for the diagnosis of oral neoplasia in a high-risk population, we characterized the in vivo autofluorescence spectra from oral submucous fibrosis (OSF) lesions and oral premalignant and malignant lesions in both OSF and non-OSF patients...

journal_title：Lasers in surgery and medicine

authors： Tsai T,Chen HM,Wang CY,Tsai JC,Chen CT,Chiang CP

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The objective of this study was to quantitatively measure changes in the elastic moduli of rabbit nasal septal cartilage during laser heating. While the efficacy of laser cartilage reshaping has been established for use in nasal surgery, few studies have investigated the temperature-dependent ...

journal_title：Lasers in surgery and medicine

authors： Chao KK,Ho KH,Wong BJ

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Lasers can be used to modify the chemical composition of dental enamel to increase the bond strength to restorative materials and to render the mineral phase more resistant to acid dissolution. Previous studies have suggested a synergistic relationship between CO(2) laser irradiation and fluor...

journal_title：Lasers in surgery and medicine

authors： Wheeler CR,Fried D,Featherstone JD,Watanabe LG,Le CQ

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:To evaluate the effect of Er:YAG and Nd:YAG laser on radicular dentine permeability when using distilled and deionized water and 1% NaClO as irrigating solutions. STUDY DESIGN/MATERIALS AND METHODS:Thirty human maxillary canines were divided randomly into six groups. The root canals were inst...

journal_title：Lasers in surgery and medicine

authors： Brugnera A Jr,Zanin F,Barbin EL,Spanó JC,Santana R,Pécora JD

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Q-switched lasers had been used in the treatment of lentigo maligna but their role remains controversial. While previous studies have addressed the change in adhesion molecule expression after sub-lethal laser damage, no study has addressed the impact of sub-lethal laser damage at a molecular ...

journal_title：Lasers in surgery and medicine

authors： Chan HH,Xiang L,Leung JC,Tsang KW,Lai KN

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Cryogen spray cooling (CSC) is used to minimize the risk of epidermal damage during laser dermatologic surgery. Since optimization of CSC permits the safe use of higher light doses, which improves therapeutic outcome in many patients with superficial skin lesions, studies have focused on under...

journal_title：Lasers in surgery and medicine

authors： Aguilar G,Wang GX,Nelson JS

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:A prospective, double-blind, randomized, and controlled trial was conducted in patients with knee osteoarthritis (OA) to evaluate the efficacy of infrared low-power Gallium-Arsenide (Ga-As) laser therapy (LPLT) and compared two different laser therapy regimes. STUDY DESIGN/MATERIALS AND METHO...

journal_title：Lasers in surgery and medicine

authors： Gur A,Cosut A,Sarac AJ,Cevik R,Nas K,Uyar A

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Laser has been reported as a heat source for melting and re-crystallization. Occurring at about 1100 degrees C, the melting of surface dental enamel along with re-crystallization might have an assistant role in the therapy of hypersensitive tooth, apical sealing of endodontic surgery in dentis...

journal_title：Lasers in surgery and medicine

authors： Wu CC,Roan RT,Chen JH

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The effects of Er:YAG laser irradiation on dentin have not been sufficiently investigated. The purpose of this study was to investigate the effects of Er:YAG laser irradiation on dentin. STUDY DESIGN/MATERIALS AND METHODS:After cavities were prepared using Er:YAG laser irradiation or rotary c...

journal_title：Lasers in surgery and medicine

authors： Ishizaka Y,Eguro T,Maeda T,Tanaka H

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To evaluate the potentials of a 1310-nm optical coherence tomography (OCT) system to penetrate the highly backscattering sclera in enucleated human eyes and provide visualization of intraocular structures by transscleral imaging. STUDY DESIGN/MATERIALS AND METHODS:OCT-images were generated by ...

journal_title：Lasers in surgery and medicine

authors： Hoerauf H,Winkler J,Scholz C,Wirbelauer C,Gordes RS,Koch P,Engelhardt R,Laqua H,Birngruber R

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:For Asian skin, recent "non-ablative" skin rejuvenation techniques have become the focus of attention for darker complected patients. In our earlier research, we have shown that intense pulsed light (IPL) technology can be applied to Asian skin with a high degree of safety and efficacy. In thi...

journal_title：Lasers in surgery and medicine

authors： Negishi K,Wakamatsu S,Kushikata N,Tezuka Y,Kotani Y,Shiba K

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Verteporfin is a new photosensitizer with short-term skin photosensitivity. The objective of this preclinical study was to find the light dose that effectively ablates canine esophageal mucosa when delivered 30 minutes after Verteporfin injection. STUDY DESIGN/MATERIALS AND METHODS:Verteporfin...

journal_title：Lasers in surgery and medicine

authors： Panjehpour M,DeNovo RC,Petersen MG,Overholt BF,Bower R,Rubinchik V,Kelly B

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In order to improve selectivity of photodynamic therapy (PDT) to choroidal neovascularization (CNV) associated with age-related macular degeneration, a laser scanning technique was applied to perform focal laser irradiation to the retina, and the occlusion effects of a new device to the chorio...

journal_title：Lasers in surgery and medicine

authors： Obana A,Gohto Y

更新日期：2002-01-01 00:00:00